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HDL remodeling and enrichment with apoCIII and apoE in Indigenous Australians

Indigenous Australians have an increased risk of type 2 diabetes mellitus and premature cardiovascular disease. Subpopulations of high-density lipoprotein (HDL) have been associated with increased cardiovascular risk, but HDL composition, size, or function have not been studied in Indigenous Australians.

Citation:
Kockx M, Wang J, Howard NJ, …….. Brown A, Kritharides L. HDL remodeling and enrichment with apoCIII and apoE in Indigenous Australians. Journal of Clinical Lipidology. 2025;19(5):1439-50.

Keywords:
HDL function; HDL remodeling; Indigenous populations

Abstract:
Indigenous Australians have an increased risk of type 2 diabetes mellitus and premature cardiovascular disease. Subpopulations of high-density lipoprotein (HDL) have been associated with increased cardiovascular risk, but HDL composition, size, or function have not been studied in Indigenous Australians.