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Efficacy of Interventions Adhering to the Revised Ayres Sensory Integration® Fidelity Measure: A Systematic Review

Sensory integration therapy is used widely despite an inconsistent evidence base. To overcome the limited availability of high-quality research, Ayres Sensory Integration (ASI) was manualized and a revised fidelity measure was developed following the identification of the principles of ASI®. The aim of this systematic review is to examine the proximal and distal effects of interventions in studies that explicitly reported the use of or adherence to the process elements of the fidelity measure. 

BEAT-BK: An Adaptive, Randomized Controlled Trial to Treat Polyomavirus Infections (BKPyV) in Kidney and Kidney-pancreas Transplantation Recipients (BEAT-BK) Study Protocol

BK polyomavirus (BKPyV) is a common opportunistic infection in kidney transplant recipients, typically reactivating in the context of immunosuppression. Although asymptomatic in immunocompetent individuals, reactivation in transplant recipients can cause BKPyV-associated nephropathy (BKPyVAN), a leading cause of graft dysfunction and loss. BKPyV viremia affects approximately 10%-15% of transplant recipients, and once BKPyVAN is established, the risk of graft failure can exceed 50%.

A Pragmatic Bayesian Adaptive Trial Design Based on the Value of Information: The Value-Driven Adaptive Design

Clinical trial designs are typically narrowly focused on error control in hypothesis testing, but this approach is inadequate in many contexts, particularly when a decision maker intends to, or must, consider multiple relevant clinical and health economic outcomes under uncertainty. Value-of-information (VoI) metrics can be used to estimate the monetary value of data collection to the decision maker. 

Unraveling intersectional risks: Postnatal adversities condition the impact of prenatal alcohol exposures on early childhood sleep outcomes

The current study aimed to examine the influence of distinct patterns of prenatal alcohol exposure and postnatal threat and deprivation during infancy on sleep outcomes at three-years. Data were derived from a longitudinal cohort originating from predominately low-income hospital settings in Australia.

Burden and Experiences of Head Lice Infestation Among Children in Western Australia

Head lice is an ectoparasitic skin infection commonly seen in primary school-aged children. In remote Australia, where rates of other skin infections and downstream sequelae are endemic, the rate of head lice infestation is unknown.

“I don't think either of us have really got over the diagnosis.” Caregiver perspectives on medical trauma in adolescent type 1 diabetes; a trauma-informed qualitative investigation

Type 1 Diabetes (T1D) is a 'family illness'; diagnoses and management can be perceived as invasive or traumatic. Caregivers bear the brunt of the diagnostic shock, influencing their child's experience. Children and adolescents may grapple with the psychological effects of past/ongoing medical trauma. Additionally, adolescents may struggle with their mental health as they navigate tensions between caregiver involvement and their developmental need for autonomy.

Impact: Research Translation

On this Research Impact page, learn about our work that's actively translated as Government policy or in active practice. Learn how our research is making a difference in people's lives - not tomorrow, next week, or next year - but today!

Intellectual Disability

About 2 per cent of children are estimated to have an intellectual disability. The cause of the condition is unknown in at least 50 per cent of cases.

Planning for a healthy start

A diet and lifestyle mobile app targeting a critical window in early pregnancy is being introduced to women in the northern suburbs of Perth, hoping to assist with breaking the ‘transmission’ of obesity from one generation to the next.

Landmark flu decision set to save kids’ lives

For the first time this year, all Australian babies and children aged six months to four years will be entitled to have a free influenza vaccination.