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Research

Prevention and Natural History of Food Allergy

The rise in food allergy is more rapid than genetic deviation would allow and the current consensus is that environmental factors integrally linked to the...

Research

Developing primary intervention strategies to prevent allergic disease

Allergic diseases are a major cause of morbidity in the developed world, now affecting up to 40 % of the population with no evidence that this is abating.

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Effects of maternal n-3 fatty acid supplementation on placental cytokines, pro-resolving lipid mediators and their precursors

The aim of this study was to determine whether supplementation with fish oil-derived n-3 PUFA during pregnancy modifies modifies placental PUFA composition...

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Blood DNA methylation biomarkers predict clinical reactivity in food-sensitized infants

The diagnosis of food allergy (FA) can be challenging because approximately half of food-sensitized patients are asymptomatic.

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Cohort profile of the HealthNuts study: Population prevalence and environmental/genetic predictors of food allergy

HealthNuts is a single-centre, multi-wave, population-based longitudinal study designed to assess prevalence, determinants, natural history and allergy...

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World Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): Probiotics

Prevalence of allergic diseases in infants, whose parents and siblings do not have allergy, is approximately 10% and reaches 20-30% in those with an allergic...

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In utero and postnatal vitamin D exposure and allergy risk

This review article examines the evidence of the impact of in utero and postnatal vitamin D exposure on allergy risk in childhood

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Hot topics in paediatric immunology: IgE-mediated food allergy and allergic rhinitis

This article focuses on IgE-mediated food allergies and allergic rhinitis, the most commonly seen conditions in paediatric immunology.

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Nutritional Influences on Epigenetic Programming. Asthma, Allergy, and Obesity

Reliance on increasing use of dietary supplementation and fortification (eg, with folate) to compensate for increased consumption of processed foods is also...

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Genome-wide DNA methylation profiling identifies a folate-sensitive region of differential methylation upstream of ZFP57-imprinting regulator in humans

This study identified that expsoure to folate has effects on the regulation of DNA methylation during fetal development.