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Progression of early structural lung disease in young children with cystic fibrosis assessed using CT

Cross-sectional studies implicate neutrophilic inflammation and pulmonary infection as risk factors for early structural lung disease in infants and young...

The anti-inflammatory actions of IL-4 in human monocytes are not mediated by IL-10, RP105 or the kinase activity of RIPK2

The anti-inflammatory actions of IL-4 in activated human monocytes may reflect transcriptional regulation of genes involved in TLR signaling pathways.

Sex dimorphism in the relation between early adiposity and cardiometabolic risk in adolescents

Birth weight and childhood adiposity are associated with subsequent cardiovascular risk. We investigated the associations between metabolic clusters in young...

Nanoparticles and Children's Lungs: Is there a need for caution?

Nanoparticle research is currently an area of considerable interest due to the potential applications both in industry and medicine.

Vitamin D supplementation, moderate sun exposure, and control of immune diseases

There is considerable debate about the benefits of vitamin D supplementation for multiple sclerosis, allergic asthma, and type 1 diabetes.

The developing respiratory tract and its specific needs in regard to ultrafine particulate matter exposure

Nanoparticles have unique physico-chemical properties compared to larger particles that have the potential to provide promising new possibilities for...

Evaluation of a new measure of mood intolerance, the Tolerance of Mood States Scale (TOMS)

This research aimed to (i) validate a new measure of mood intolerance, the Tolerance of Mood States (TOMS) scale, and (ii) to examine associations between...

Suppression of adrenomedullin contributes to vascular leakage and altered epithelial repair during asthma

The anti-inflammatory peptide, adrenomedullin (AM), and its cognate receptor are expressed in lung tissue, but its pathophysiological significance in airway...

Risk of childhood acute lymphoblastic leukaemia following parental occupational exposure to pesticides

Risk of childhood acute lymphoblastic leukaemia following parental occupational exposure to pesticides.

The association between neighborhood greenness and cardiovascular disease: An observational study

Previous studies have demonstrated links between cardiovascular disease and physical inactivity and poor air quality, which are both associated with...