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Wet cough prevalence among Aboriginal children ‘concerningly high’The Kids Research Institute Australia and Perth Children’s Hospital clinician-researchers have found more than one in ten children across four remote Kimberley communities have protracted bacterial bronchitis.
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Decoding Susceptibility to Respiratory Viral Infections and Asthma Inception in ChildrenHuman Respiratory Syncytial Virus and Human Rhinovirus are the most frequent cause of respiratory tract infections in infants and children and are major triggers of acute viral bronchiolitis, wheezing and asthma exacerbations.
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The Respiratory Microbiome in Paediatric Chronic Wet Cough: What Is Known and Future DirectionsChronic wet cough for longer than 4 weeks is a hallmark of chronic suppurative lung diseases, including protracted bacterial bronchitis, and bronchiectasis in children. Severe lower respiratory infection early in life is a major risk factor of PBB and paediatric bronchiectasis.
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Reference exome data for a Northern Brazilian populationExome sequencing is widely used in the diagnosis of rare genetic diseases and provides useful variant data for analysis of complex diseases. There is not always adequate population-specific reference data to assist in assigning a diagnostic variant to a specific clinical condition.
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Protection against neonatal respiratory viral infection via maternal treatment during pregnancy with the benign immune training agent OM-85Incomplete maturation of immune regulatory functions at birth is antecedent to the heightened risk for severe respiratory infections during infancy. Our forerunner animal model studies demonstrated that maternal treatment with the microbial-derived immune training agent OM-85 during pregnancy promotes accelerated postnatal maturation of mechanisms that regulate inflammatory processes in the offspring airways.
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The association between preschooler physical activity duration and intensity and social emotional development: Findings from the PLAYCE studySocial emotional development is imperative to young children's long-term psychological and physical health. Physical activity (PA) may be important for young children's social emotional development. The association between preschooler PA duration and intensity and social emotional development was investigated.
News & Events
Wet cough campaign aims to nip lung disease in the budThe Kids Research Institute Australia lung health researchers have launched a campaign to raise awareness of wet cough and lung disease in Aboriginal children.
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Herpes simplex virus in infancy: Evaluation of national surveillance case captureAs herpes simplex virus in infancy is not a mandatory notifiable condition in Australia, completeness of ascertainment by the Australian Paediatric Surveillance Unit (APSU) has been difficult to evaluate to date. We evaluated case capture in Queensland and Western Australia using statewide laboratory and clinical data and complementary surveillance data collected via the APSU.
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An observational study of antibody responses to a primary or subsequent pertussis booster vaccination in Australian healthcare workersAdult pertussis vaccination is increasingly recommended to control pertussis in the community. However, there is little data on the duration and kinetics of immunity to pertussis boosters in adults. We compared IgG responses to vaccination with a tetanus, low-dose diphtheria, low-dose acellular pertussis (Tdap) booster at 1 week, 1 month and 1 year post-vaccination in whole-cell (wP)-primed Australian paediatric healthcare workers who had received an adult Tdap booster 5-12 years previously, to those who received their first Tdap booster. Tdap vaccination was well tolerated in both groups.
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Respiratory Viral Testing Rate Patterns in Young Children Attending Tertiary Care Across Western Australia: A Population-Based Birth Cohort StudyBelaynew Christopher Peter Hannah Minda Huong Taye Blyth Richmond Moore Sarna Le MD, MPH, PhD MBBS (Hons) DCH FRACP FRCPA PhD MBBS MRCP(UK) FRACP OAM
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Frequency of protracted bacterial bronchitis and management pre-respiratory referralTo determine the frequency of protracted bacterial bronchitis (PBB) in children referred to tertiary care with chronic cough and describe management prior to referral. A retrospective cohort study of all new patients with a history of ≥4 weeks of cough seen at the only tertiary paediatric outpatient respiratory service in Western Australia.
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ORIGINS: Nutritional Profile of Children Aged One Year in a Longitudinal Birth CohortDietary intake during the first year of life is a key determinant of a child's growth and development. ORIGINS is a longitudinal birth cohort study investigating factors that contribute to a 'healthy start to life' and the prevention of non-communicable diseases.
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Cough in Children and Adults: Diagnosis, Assessment and Management (CICADA). Summary of an updated position statement on chronic cough in AustraliaCough is the most common symptom leading to medical consultation. Chronic cough results in significant health care costs, impairs quality of life, and may indicate the presence of a serious underlying condition. Here, we present a summary of an updated position statement on cough management in the clinical consultation.
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Chronic wet cough in Aboriginal children: It's not just a coughResults highlight the need for a culturally appropriate information and education of the importance of chronic wet cough in children
News & Events
Key appointments to drive early childhood collaborationLeading child health researcher Professor Donna Cross has been appointed as Director of the new Early Childhood Development and Learning Collaboration, hosted b
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The Kids welcomes Minderoo investment in early child developmentThe Kids has congratulated Andrew & Nicola Forrest on their visionary commitment to develop a new blueprint for optimal child development in Aust & beyond.
News & Events
Early Years Initiative an unprecedented commitment to youngest West AustraliansMinderoo Foundation and The Kids Research Institute Australia are proud to partner with the Western Australian Government on an unprecedented $49.3 million commitment to
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The Kids researchers awarded Raine Medical Research Foundation fundingCongratulations to Dr Gail Alvares and Dr Rachel Foong, who have been awarded funding from the Raine Medical Research Foundation.
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Does perinatal exposure to exogenous oxytocin influence child behavioural problems and autistic-like behaviours to 20 years of ageThis study is the first to investigate longitudinal mental health outcomes associated with the use of oxytocin-based medications during labour
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A realist evaluation of peer mentoring support for university students with autismStandard peer mentoring approaches can be enhanced to meet the needs of students with ASD by including training for mentors on ASD
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Inner speech impairments in autismThree experiments investigated the role of inner speech deficit in cognitive performances of children with autism.
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Beyond the hype and hope: Critical considerations for intranasal oxytocin research in autism spectrum disorderIn this review, we comprehensively evaluate the rationale for oxytocin as a therapeutic, evaluating evidence from various various sources.