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Research
Geographical migration and fitness dynamics of Streptococcus pneumoniaeStreptococcus pneumoniae is a leading cause of pneumonia and meningitis worldwide. Many different serotypes co-circulate endemically in any one location. The extent and mechanisms of spread and vaccine-driven changes in fitness and antimicrobial resistance remain largely unquantified.
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Randomized Trial of BCG Vaccine to Protect against Covid-19 in Health Care WorkersThe bacille Calmette-Guérin (BCG) vaccine has immunomodulatory "off-target" effects that have been hypothesized to protect against coronavirus disease 2019.
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PneuMum: Impact from a trial of maternal pneumococcal vaccination on middle ear disease amongst Indigenous infantsThis study was unable to demonstrate efficacy of 23vPPV in pregnancy against the co-primary outcomes of either all-cause infant ear disease.
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Continuous active surveillance of adverse events following immunisation using SMS technologyAutomated SMS-based reporting can facilitate sustainable, real-time, monitoring of adverse reactions and early identification of potential vaccine safety issues
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Transiently increased IgE responses in infants and pre-schoolers receiving only (DTaP) vaccines compared to those initially receiving at least one dose of DTwP vaccineConfirm the generalised IgE-trophic activity of the DTaP vaccine in pre-schoolers and demonstrate similar (albeit transient) effects in infants
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Safety and immunogenicity of a vero cell culture-derived whole-virus influenza a(H5N1) vaccine in a pediatric populationThis study examined the safety and immunogenicity of a vero cell culture-derived whole-virus influenza a(H5N1) vaccine in a pediatric population.
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Safety and tolerability of a 2009 trivalent inactivated split-virion influenza vaccine in infants, children and adolescentsTo evaluate the safety of CSL's split-virion inactivated trivalent 2009 Southern Hemisphere formulation influenza vaccine (TIV) in children.
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Genome-wide association study of IgG1 responses to the choline-binding protein PspC of Streptococcus pneumoniaeDelayed development of antibodies to S. pneumoniae in infancy is associated with the development of atopy and asthma.
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Position statement of the World Heart Federation on the prevention and control of rheumatic heart diseaseIn the 21st century, rheumatic fever (RF) and rheumatic heart disease (RHD) are neglected diseases of marginalized communities.
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TLR3 and RIG-I gene variants: Associations with functional effects on receptor expression and responses to measles viruMeasles virus causes severe morbidity and mortality, despite the availability of measles vaccines. Successful defence against viral pathogens requires early...